Acne Relief Prebiotic Acne Therapy 90-Day Regimen

What Really Causes Acne?

Excess oil, acne-causing bacteria and inflammation are the culprits, and you need to treat all three.

Unlike most other acne treatment systems on the market, Perricone MD Acne Relief selectively targets and gently treats all three causes of acne - excess oil, acne-causing bacteria and inflammation. Many other brands rely on harsh chemicals that just kill all bacteria, or aggressively strip your skin of necessary hydration, which can upset skin’s natural microbiome and lead to irritation and dryness.  Rather than wash away all oil and bacteria, Acne Relief is designed to work symbiotically with skin’s microbiome to remove excess oil while simultaneously depositing hydrators that won’t dry skin out. 

Our Prebiotic Approach

Understand the science and benefits behind creating a healthy microbiome and balanced skin.

The patent-pending science behind Acne Relief is our prebiotic approach, a system that adapts to your skin’s unique microbiome to target troublesome acne. Using naturally occurring prebiotics, Acne Relief helps your skin safely and gently fight back against acne without disrupting its natural balance. The result? An effective defense against acne-causing bacteria that promotes a clear, blemish-free complexion.

Below are some of the key ingredients in Acne Relief behind our prebiotic approach:

Sucrose: Exfoliate & Support a Healthy Skin Biome

Milled to an ultra-fine sugar, this mild exfoliant helps unclog pores and remove excess dirt and oil without over-drying or stripping skin. Sucrose helps support a healthy skin biome by encouraging good bacteria and rinses off quickly and easily, making it ideal for gentle yet effective cleansing.

Citrulline: Fight Irritation & Visibly Reduce Redness

First discovered in watermelon, this alpha-amino acid visibly calms skin for a clearer, more even-looking complexion. Nourishing and soothing, it is an ideal way to counteract irritation.

Lactic & Succinic Acids: Attack Acne-Causing Bacteria

These short-chain fatty acids help quickly shrink blemishes by working alongside salicylic acid to attack acne-causing bacteria for a healthier skin microbiome. They also provide gentle yet effective exfoliation for smoother, more even-looking skin.

Niacinamide: Gentle Skin-Clearing Multi-Tasker

Also known as vitamin B3 and found in foods such as tomatoes, this skin-clearing powerhouse helps to gently and visibly erase imperfections, unclog oily pores and minimize uneven skin tone that can be left behind after breakouts by improving skin’s moisture barrier. Niacinamide is one of the essential vitamins skin needs to maintain a youthful look.

Squalane: Hydrate & Nourish

Found naturally in the human body and derived from olive oil, squalane hydrates without making skin look or feel greasy. This lightweight hydration is ideal for oil and acne-prone skin as it helps maintain optimal hydration without leaving skin feeling greasy and clogged.

Salicylic Acid: Pore-Minimizing, Anti-Acne Exfoliation

A beta-hydroxy acid (BHA), salicylic acid is a non-prescription treatment for acne and oil-prone skin. It quickly and effectively exfoliates and removes dead skin which can clog pores and cause breakouts. Because it is oil-soluble, salicylic acid is easily absorbed into pores for targeted, more effective results.

Retinol: Exfoliate for Clearer Skin & Accelerated Rejuvenation

This ultra-powerful, non-prescription vitamin A derivative helps prevent breakouts by unclogging pores and accelerating surface skin exfoliation and renewal. Retinol is the #1 dermatologist recommended, non-prescription skin-aging solution.

Acne Relief Gentle & Soothing Cleanser

Glycerin, Sodium Cocoyl Isethionate, Ethylhexyl Palmitate, Silica Cetyl Silylate, Sucrose, Squalane, Polyacrylamide, Water/ Aqua/Eau, Caprylyl Glycol, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol

Acne Relief Calming Treatment & Hydrator

Water/Aqua/Eau, SD Alcohol 40-B, Glycerin, C12-15 Alkyl Lactate, PVP, Dimethicone, Polysorbate 20, Citrulline, Squalane, Lactic Acid, Succinic Acid, Polyacrylamide, Dimethicone/Vinyl Dimethicone Crosspolymer, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate

Acne Relief Retinol Treatment & Moisturizer

Water/Aqua/Eau, SD Alcohol 40-B, Glycerin, Dicaprylyl Ether, Niacinamide, Citrulline, Arginine, Methyl Gluceth-20, Cetearyl Alcohol, Carbomer, Xanthan Gum, Tocopheryl Acetate, Retinol, Citric Acid, Sodium Hydroxide, Disodium EDTA, PEG-20 Methyl Glucose Sesquistearate, PEG-100 Stearate, Glyceryl Stearate, Methyl Glucose Sesquistearate, Polysorbate 20, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate

Step 1: Day & Night Acne Relief Gentle & Soothing Cleanser

Lather a quarter-sized amount in hands & gently massage onto damp skin. Rinse thoroughly with warm water. For best results, follow with ACNE RELIEF Calming Treatment & Hydrator in the morning & ACNE RELIEF Retinol Treatment & Moisturizer in the evening.

Step 2: Day  Acne Relief Calming Treatment & Hydrator

Shake well. Apply a thin, even layer to skin in the morning. For best results, use after cleansing with ACNE RELIEF Gentle & Soothing Cleanser.

Step 2: Night Acne Relief Retinol Treatment & Moisturizer

Shake well. Apply a thin, even layer to skin in the evening. For best results, use after cleansing with ACNE RELIEF Gentle & Soothing Cleanser.