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High Potency. This collection address lines, wrinkles, uneven texture and tone, as well as loss of firmness with the full force of out signature sciences.

FEATURED HIGH POTENCY PRODUCTS

FACE FINISHING & FIRMING RADIANT MOISTURIZER

A limited-edition version of our bestselling firming moisturizer that delivers instant radiance as it visibly minimizes imperfections, uneven texture and discoloration.
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INTENSIVE SMOOTHING SERUM

Visibly smooths rough skin texture for a more refined, even-looking complexion.
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HYALURONIC INTENSIVE HYDRATING MASK

Instantly nourishes and hydrates for a visibly plump and smooth complexion.
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THE SCIENCE OF HIGH POTENCY

Image of High Potency Jar. Tighten and enlarges pores. Diminishes fine lines & wrinkles. Refines and smoothes uneven texture.

TARGETED SOLUTIONS FOR LINES, WRINKLES & ENLARGED PORES

Formulated with high concentrations of Perricone MD's signature sciences, the High Potency Collection provides targeted solutions for more youthful, healthier-looking skin. Each formula is designed to help visibly tighten pores and visibly minimize the length, depth and width of fine lines and wrinkles using some of our most advanced age-defying ingredients.
Image of High potency ingredients. Alpha-Lipoic Acid. Reduces the appearance of lines, wrinkles and enlarged pores over time. DMAE. Visibly plumps skin to help support skin's surface and protect against drying environmental aggressors.

UNDERSTANDING THE SCIENCES

Featuring Alpha-Lipoic Acid (ALA) and DMAE.
ALA, nature’s most powerful antioxidant, is a fatty acid found in every cell in the human body that penetrates skin’s surface to help reduce the appearance of lines, wrinkles and enlarged pores over time.
DMAE, naturally produced by the human brain, helps visibly lift sagging skin over time. Easily and quickly absorbed, it helps visibly plump skin to support skin’s surface structure and protect against drying environmental aggressors
Image of High potency Intensive Trio Box set.

THE INTENSIVE TRIO STARTER COLLECTION

The perfect way to try the High Potency Collection, the Intensive Trio is designed for skin that requires more targeted solutions. Formulated with Alpha-Lipoic Acid, DMAE and polyamine growth factor to reduce the appearance of fine lines and wrinkles and to smooth uneven skin texture.

SHOP THE HIGH POTENCY COLLECTION
HIGH POTENCY RETINOL RECOVERY OVERNIGHT MOISTURIZER

FEATURED HIGH POTENCY REGIMENS

LIFT & PLUMP HYDRATION DUO
$158 (value $210)

A duo comprised of our powerful day-to-night anti-wrinkle serum and our indulgent, nourishing firming moisturizer to deeply hydrate the skin for a visibly plump, radiant appearance.

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CLASSIC FIRMING DUO
$159 (value $180)

A powerhouse anti-wrinkle treatment paired with our indulgent moisturizer to visibly smooth and minimize the appearance of wrinkles for radiant skin.


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FAN FAVORITE SIGNATURE REGIMEN
$209 (value $269)

A trio comprised of a gentle cleanser, our best-selling moisturizer and a multi-tasking powerhouse for healthy, youthful-looking skin.


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LIFT & PLUMP INTENSIVE HYDRATION REGIMEN
$186 (value $249)

A multi-tasking regimen for day to night nourishment, gentle cleansing and intense moisturizer that leaves skin revitalized.


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FOR FURTHER READING

GROWTH FACTOR: YOUR SKIN'S OWN PERSONAL INFLUENCER

Social media may have made “influencer” one of the most ubiquitous professions of our digital era, but when it comes to the OG of having an effect on behavior, that distinction goes to growth factors.
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DON'T BELIEVE THE MYTHS: GETTING TO THE FACTS ABOUT HYALURONIC ACID.

Even if you’re a skincare newbie, you’ve probably heard a thing or two about hyaluronic acid (HA) as it’s gained popularity in recent years. And rightfully so! It’s worth all the hype.
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INTRODUCING HIGH POTENCY SKINCARE: THE SCIENCE-BACKED COLLECTION TO MORE EVEN, SMOOTHER SKIN

With the promise of transparency, efficacy studies and results, research-backed brands like Perricone MD are here to stay. In fact, we’ve taken a science-backed approach since the very beginning when Dr. Nicholas Perricone created our very first High Potency Collection.
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