FREE US SHIPPING $150+ GIFT WITH PURCHASE PERRICONE PLUS+ REWARDS BUY NOW, PAY LATER WITH AFTERPAY
Happy Valentines Day - Buy one, get one free on select products - Use code: LOVE | SHOP NOW ▶︎
Acne Relief. A simple , 2-step skincare system that works with your skin's natural microbiome to target and safely, yet effectively, treat three causes of acne.

Product Spotlight

ACNE RELIEF MAXIMUM STRENGTH CLEARING TREATMENT
$35

This lightweight cream is formulated with maximum strength salicylic acid in a sustained delivery system for less irritation to target the most stubborn acne. Combined with a biomimetic oat protein, skin-soothing cica and lactobacillus ferment to help calm flare-ups, visibly reduce skin redness and selectively target acne-causing bacteria for a visibly clear, smooth and healthy complexion.

SHOP NOW

ACNE RELIEF PREBIOTIC ACNE THERAPY 30-DAY REGIMEN
$39 (VALUE $43)

Try our Acne Relief 30-Day Regimen risk-free today. This simple, comprehensive system works with your surface skin’s natural microbiome to safely, gently and effectively treat and prevent the most troublesome acne, while restoring and maintaining a healthy skin balance for visibly clear skin. This powerful, 2-step regimen is clinically proven to be non-irritating and will not strip or over-dry the skin.

SHOP NOW

LEARN MORE ABOUT ACNE RELIEF

What really causes acne? inflammation, acne causing bacteria, inflammation, excess oil.

WHAT REALLY CAUSES ACNE?

Unlike most other acne treatment systems on the market, Perricone MD Acne Relief selectively targets and gently treats all three causes of acne: excess oil, acne-causing bacteria and inflammation.
Target bad bacteria, Keep Good bacteria.

OUR PREBIOTIC APPROACH

The patent-approved science behind Acne Relief is our prebiotic approach, a system that adapts to your skin’s unique microbiome, or natural environment, by targeting the bad bacteria and keeping the good bacteria. Maintaining a healthy microbiome and balancing skin is key to keeping skin clear and functioning properly.
Image of ingredients. Sucrose exfoliates and supports a healthy skin biome. Citrulline, fights irritation and visibly reduces redness. Niacinamide, renews and restores

THE PREBIOTIC INGREDIENTS

Using naturally occurring prebiotics like sucrose, citrulline and niacinamide, Acne Relief helps your skin safely and gently fight back against acne without disrupting its natural balance. The result? An effective defense against acne-causing bacteria that promotes the appearance of a clear, blemish-free complexion.

REAL PEOPLE, REAL RESULTS.

"Best $ I have ever spent!"

My daughters acne showed up out of no where. We tried everything and anything anyone suggested and nothing worked. I finally started doing my own research online and came across Perricone MD.... Thank you!
-Mo

"I am definitely buying this again!"

I absolutely love the simplicity of this acne system. Having acne into my late 20's now, it's so nice to find a line that isn't 6+ steps long...
-Tally

"This product is the TRUTH!"

....not even 60 days into the kit and my acne started clearing up tremendously, and I've never loved my skin so much.
-Trin

"A life saver!"

I used Perricone treatment morning and night and it only took a week for my acne to subside....I've been having horrible acne since my son was born and this is the first product line to offer real help!
-Mrs. O

SHOP THE ACNE RELIEF COLLECTION
Showing slide 1

LEARN MORE ABOUT HOW ACNE RELIEF WORKS

LEARN MORE ABOUT HOW ACNE RELIEF WORKS

Take a closer look at the science behind this simple, comprehensive system that works with your surface skin’s natural microbiome to safely, gently and effectively treat and prevent the most troublesome acne, while restoring and maintaining a healthy skin balance for clearer, blemish-free skin.

FOR FURTHER READING

WHAT REALLY CAUSES ACNE? THE 3 MAIN CULPRITS

If you suffer from acne, you’ve probably heard it all: It’s all that greasy food you eat! You’re too stressed! Your skin isn’t clean enough! Yup, there are a lot of theories out there about what’s really behind your breakouts, but a good deal of them are nothing more than fake news.

 

 

 
READ MORE

BREAKING OUT FROM YOUR MASK? HERE'S HOW TO BEAT MASKNE

We don’t have to tell you that masks are a must these days. Medical experts say wearing a paper or cloth mask in public spaces is one of the most important things we can do to slow the spread of COVID-19. What’s not a must? The telltale pimples on your cheeks and chin caused by all that mask wearing.
READ MORE

PIMPLE, BLACKHEAD, & WHITEHEADS, WHATS THE DIFFERENCE?

Pimples, Blackheads, Whiteheads. No doubt you’ve heard these terms numerous times, and likely personally dealt with them. People often use the terms pimples, whiteheads, blackheads, and acne synonymously. From a clinical standpoint, blackheads and whiteheads are two types of pimples, both of which are a symptom of acne.
READ MORE