Game-Changing Serums: 4 Clinically Proven Treatments for Your Specific Skin Concerns

Whether your skin is in need of a hydration boost, supercharged brightening or reduction in fine lines and wrinkles, it’s essential to choose a targeted treatment (or a few) to address your specific skin concerns.

Try this carefully curated selection of serums for personalized results depending on your skin’s needs. Plus, maximize their benefits with practical tips courtesy of Perricone MD Director of Education, Rosalba Martone.

Essential Fx Acyl-Glutathione Deep Crease Serum

Rosalba’s Recommendation: “Spend a few extra seconds massaging the product into deep creases and deep wrinkles that are already visible on the skin.”

Highly potent, silky and luxurious, this deep crease serum absorbs quickly to visibly smooth stubborn, deep-set lines, wrinkles and creases around your mouth, eyes, lips and forehead. Using skin-smoothing Acyl-Glutathione and a barrier-supporting vitamin F blend, it helps improve the appearance of imperfections and expression lines for a more even, crease-less complexion. 

High Potency Triple Retinol Renewal Serum

Rosalba’s Recommendation: “Layer with a hyaluronic acid moisturizer, like our Hyaluronic Intensive Moisturizer, for added nourishment.”

Our most powerful retinol yet is powered by a unique formula that delivers visibly firm, collagen-rich skin without irritation. While our proprietary Triple Retinol Blend gently accelerates surface skin renewal in 3 days, beta-carotene protects those concentrated retinol levels and coenzyme Q10 (COQ10) neutralizes free radicals for maximum stability and efficacy.

Vitamin C Ester CCC + Ferulic Brightening Complex 20%

Rosalba’s Recommendation: “For added crease reduction, follow with Deep Crease Serum.”

This supercharged serum features our highest concentration of vitamin C to brighten, minimize discoloration and even skin texture. The illuminating Vitamin C Ester and nourishing vitamin E in this formula work in tandem with ferulic acid, which is known to stabilize these vitamins and enhance their properties for maximum benefits. The result is a brighter, smoother, more even-toned complexion.

High Potency Hyaluronic Intensive Hydrating Serum

Rosalba’s Recommendation: “Apply on damp skin for maximum hydrating benefits from the hyaluronic acid.”

Designed with four forms and two natural building blocks of ultra-hydrating hyaluronic acid, this serum instantly replenishes essential moisture for visibly smoother, firmer and plumper skin. Also formulated with firming DMAE and restorative niacinamide, it’s a must-have treatment for supporting and maintaining a healthy skin barrier while improving skin cushion and reducing the look of lines and wrinkles.

Unbox all four of these clinically proven treatments for just $75 ($225 value) when you subscribe to April’s Skincare Edit, a Perricone MD monthly beauty box subscription featuring a special curation of new must-haves and existing customer favorites.